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G2901

Sigma-Aldrich

Gly-Pro p-nitroanilide p-toluenesulfonate salt

chromogenic, ~99% (TLC), powder

Synonym(s):

GPDA, Gly-Pro-pNA TosOH

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O4 · C7H8O3S
CAS Number:
65096-46-0
Molecular Weight:
464.49
MDL number:
MFCD00039007
UNSPSC Code:
12352204
PubChem Substance ID:
329799907
NACRES:
NA.32

product name

Gly-Pro p-nitroanilide p-toluenesulfonate salt, ~99% (TLC)

Assay

~99% (TLC)

form

powder

solubility

1 M HCl: 50 mg/mL

storage temp.

−20°C

SMILES string

Cc1ccc(cc1)S(O)(=O)=O.NCC(=O)N2CCC[C@H]2C(=O)Nc3ccc(cc3)[N+]([O-])=O

InChI

1S/C13H16N4O4.C7H8O3S/c14-8-12(18)16-7-1-2-11(16)13(19)15-9-3-5-10(6-4-9)17(20)21;1-6-2-4-7(5-3-6)11(8,9)10/h3-6,11H,1-2,7-8,14H2,(H,15,19);2-5H,1H3,(H,8,9,10)/t11-;/m0./s1

InChI key

XHLUWCXVWCBOPP-MERQFXBCSA-N

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Application

Gly-Pro p-nitroanilide p-toluenesulfonate salt has been used as a substrate to assay dipeptidyl peptidase IV (DPPIV) activity in serum, and brush border homogenates.

Substrates

Substrate for Dipeptidyl Peptidase IV.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ivana Z Matić et al.
Leukemia & lymphoma, 54(12), 2701-2706 (2013-03-09)
The aim of this research was to determine the serum dipeptidyl peptidase IV (DPPIV) activity as well as the percentages of CD26 + lymphocytes and CD26 + overall white blood cells in patients with hematological malignancies: non-Hodgkin lymphoma (NHL), Hodgkin
Delphine Ley et al.
Scientific reports, 9(1), 18111-18111 (2019-12-04)
The first thousand days of life are a critical time of development in humans during which the risk profile for diseases in later life can be modified. Nevertheless, long-term consequences of early environment on susceptibility to intestinal diseases have not
Ivana Z Matić et al.
BMC immunology, 13, 48-48 (2012-08-23)
Dipeptidyl peptidase IV, a multifunctional serine protease, is implicated in regulation of malignant transformation, promotion and further progression of cancer, exerting tumor-suppressing or even completely opposite - tumor-promoting activities. The aim of present research was to determine the serum DPPIV
Delphine Ley et al.
Scientific reports, 9(1), 18111-18111 (2019-12-04)
The first thousand days of life are a critical time of development in humans during which the risk profile for diseases in later life can be modified. Nevertheless, long-term consequences of early environment on susceptibility to intestinal diseases have not
Anna Iwaniak et al.
International journal of molecular sciences, 22(6) (2021-04-04)
In silico and in vitro methods were used to analyze ACE- and DPP-IV-inhibiting potential of Gouda cheese with a modified content of β-casein. Firstly, the BIOPEP-UWM database was used to predict the presence of ACE and DPP-IV inhibitors in casein

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