C1879

Choline chloride

≥98%

• Synonym(s): (2-Hydroxyethyl)trimethylammonium chloride
• Linear Formula: (CH₃)₃N(Cl)CH₂CH₂OH
• CAS Number: 67-48-1
• Molecular Weight: 139.62
• Beilstein: 3563126
• EC Number: 200-655-4
• MDL number: MFCD00011721
• UNSPSC Code: 12352200
• PubChem Substance ID: 57653990
• NACRES: NA.77

Properties

• biological source: synthetic
• Quality Level: 200
• Assay: ≥98%
• form: powder or crystals
• technique(s): cell culture | mammalian: suitable
• color: colorless to white
• mp: 302-305 °C (dec.) (lit.)
• SMILES string: [Cl-].C[N+](C)(C)CCO
• InChI: 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
• InChI key: SGMZJAMFUVOLNK-UHFFFAOYSA-M

Description

General description

Choline chloride is the synthetic form of vitamin B4, choline and is a common poultry feed.[1]

Application

Choline chloride has been used:

• as a substrate for measuring choline oxidase enzyme activity using fluorescence measurements[2]
• as a component of non-physiological buffers for testing calcium based inhibition of cytochrome c oxidaseP[3]
• as a component of perfusate solution for studying arterial pressure in jejunum samples[4]

Biochem/physiol Actions

Choline chloride treatment of radish seeds modulates phosphatidylcholine and phosphatidylethanolamine levels.[5] It elicits hepatoprotective effects and modulates methyl carbon based metabolic pathways.[6]

Substrates

Choline acetyltransferase substrate

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves