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81440

Sigma-Aldrich

Polyvinylpyrrolidone

K 90

Synonym(s):

PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Quality Level

form

powder or crystals (or flakes)

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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Application

Polyvinylpyrrolidone (PVP),also known as K90 is a water soluble polymer with good bio-stability. It is chemically stable, has low toxicity and is biocompatible. Hence, it is useful in a variety of applications such as cosmetics, tissue engineering, and biomedical engineering.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A high flux ultrafiltration membrane spun from PSU/PVP (K90)/DMF/1, 2-propanediol
Qin J, et al.
Journal of Membrane Science , 211(1), 139-147 (2003)
Development of poly (l-lactic acid) hollow fiber membranes for artificial vasculature in tissue engineering scaffolds
Bettahalli NMS, et al.
Journal of Membrane Science , 371(1-2), 117-126 (2011)
Mass and controlled fabrication of aligned PVP fibers for matrix type antibiotic drug delivery systems
Wang L, et al.
Chemical Engineering Journal, 307, 661-669 (2017)
Nicole M Sanders et al.
American journal of physiology. Endocrinology and metabolism, 294(5), E853-E860 (2008-03-13)
Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed for patients with comorbid diabetes and depression. Clinical case studies in diabetic patients, however, suggest that SSRI therapy may exacerbate hypoglycemia. We hypothesized that SSRIs might increase the risk of hypoglycemia by
Massimiliano di Cagno et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(4-5), 775-780 (2013-01-29)
The objective of this study was to investigate if the increase in apparent solubility induced by liposomalization or micellization of the poorly soluble drug hydrocortisone (HC) would lead to an enhancement of its permeability through biological membranes. For this purpose

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