K2755

2-Keto-3-deoxyoctonate ammonium salt

≥97%

• Synonym(s): 3-Deoxyoctulosonic acid, KDO
• Linear Formula: C₈H₁₄O₈ · NH₃
• CAS Number: 103404-70-2
• Molecular Weight: 255.22
• MDL number: MFCD00057549
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654316
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥97%
• form: powder
• storage temp.: −20°C
• SMILES string: N.OCC(O)C1OC(O)(CC(O)C1O)C(O)=O
• InChI: 1S/C8H14O8.H3N/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14;/h3-6,9-12,15H,1-2H2,(H,13,14);1H3
• InChI key: UDJBBKGYARWWNJ-UHFFFAOYSA-N

Description

Application

• Synthesis of KDO Analogues: A significant study focused on the synthesis of analogues of 3-deoxy-D-manno-octulosonic acid (KDO), which includes compounds such as 2-Keto-3-deoxyoctonate ammonium salt. These analogues were evaluated as potential inhibitors of CMP-KDO synthetase, playing a critical role in the development of new therapeutic agents targeting bacterial infections and enhancing understanding of bacterial lipopolysaccharide synthesis (Luthman et al., 1987).

Biochem/physiol Actions

KDO is a sialic acid that is a component of bacterial lipopolysaccharides and a possible target for antibiotic development.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves