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Key Documents

B2753

Sigma-Aldrich

Butyrylcholine chloride

≥98%

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About This Item

Linear Formula:
C9H20NO2Cl
CAS Number:
Molecular Weight:
209.71
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98%

form

powder

storage temp.

−20°C

SMILES string

O.[Cl-].CCCC(=O)OCC[N+](C)(C)C

InChI

1S/C9H20NO2.ClH/c1-5-6-9(11)12-8-7-10(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1

InChI key

VCOBYGVZILHVOO-UHFFFAOYSA-M

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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[Treatment of Alzheimer's disease: status quo and future considerations].
Shun Shimohama
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 131(5), 351-356 (2008-05-16)
S Darvesh et al.
Journal of the autonomic nervous system, 71(2-3), 75-84 (1998-10-06)
Cholinergic neurotransmission plays a significant role in intrinsic cardiac ganglia with the action of acetylcholine being terminated by acetylcholinesterase (AChE, EC 3.1.1.7). Anatomical studies were performed to characterize neurons associated with AChE and a closely related enzyme, butyrylcholinesterase (BuChE, EC
G Petroianu et al.
Journal of toxicology. Clinical toxicology, 39(1), 27-31 (2001-05-01)
Intoxications with organophosphorous compounds, especially paraoxon, are frequent. Organophosphorous compounds inhibit serine hydrolases such as acetylcholine, butyrilcholine, and carboxyl esterases although acetylcholine and butyrylcholine are too sensitive to paraoxon to be useful markers of severity. They cannot show a dose-dependent
Sultan Darvesh et al.
Experimental neurology, 188(2), 461-470 (2004-07-13)
Cholinesterase inhibitors used to treat the symptoms of Alzheimer's disease (AD) inhibit both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), albeit to different degrees. Because central and peripheral neurons, including intrinsic cardiac neurons located on the surface of the mammalian heart, express
M Watanabe et al.
Biochemical medicine and metabolic biology, 36(3), 355-362 (1986-12-01)
Acetylcholine levels of whole blood from 80 healthy subjects were determined by pyrolysis-gas chromatography-mass fragmentography. Acetylcholine was extracted from 1.2 ml of venous blood in the presence of eserine, demethylated by pyrolysis, and assayed by selected ion-current monitoring using butyrylcholine

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