494127-M

Ghrelin, Rat, Mouse, Synthetic

The 28-amino acid n-octanoylated (at ser3) natural peptidyl ligand for the growth hormone secretagogue receptor 1a (GHSR1a).

• Synonym(s): Ghrelin, Rat, Mouse, Synthetic, GS-S(n-octanoyl)-FLSPEHQKAQQRKESKKPPAKLQPR
• Empirical Formula (Hill Notation): C₁₄₇H₂₄₅N₄₅O₄₂
• Molecular Weight: 3314.79
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• color: white
• solubility: water: 1 mg/mL
• storage temp.: 2-8°C

Description

General description

The 28-amino acid n-octanoylated (at ser3) natural peptidyl ligand for the growth hormone secretagogue receptor 1a (GHSR1a). Ghrelin is secreted predominantly in the stomach and stimulates growth hormone release from the pituitary gland. Rat and mouse ghrelin differ from that of human (Cat. No. 494126) by only two amino acids.

Warning

Toxicity: Standard Handling (A)

Sequence

H-Gly-Ser-Ser(Octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Ukkola, O. 2009. Curr. Protein Pept. Sci.10, 2.
Kojima, M., et al. 1999. Nature402, 656.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany