1.06577

tri-Sodium phosphate dodecahydrate

EMPROVE^® ESSENTIAL, NF, E 339

• Synonym(s): tri-Sodium phosphate dodecahydrate, Sodium phosphate tribasic, Trisodium phosphate
• Empirical Formula (Hill Notation): Na₃O₄P · 12H₂O
• CAS Number: 10101-89-0
• Molecular Weight: 380.12
• MDL number: MFCD00149198
• UNSPSC Code: 12352302
• E Number: E339
• EC Index Number: 231-509-8

Properties

• agency: NF
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 12 (20 °C, 10 g/L in H₂O)
• mp: 75 °C (Elimination of water of crystallisation)
• solubility: 285 g/L
• density: 1.62 g/cm³ at 20 °C
• application(s): liquid formulation; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/3Na.H3O4P.12H2O/c;;;1-5(2,3)4;;;;;;;;;;;;/h;;;(H3,1,2,3,4);12*1H2/q3*+1;;;;;;;;;;;;;/p-3
• InChI key: ASTWEMOBIXQPPV-UHFFFAOYSA-K

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Sodium phosphate dodecahydrate is used as a buffering agent for liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable