54127-U

2-(2-Pyridyl)ethyl Silica Gel

bed wt 100 mg, volume 1 mL, pk of 108

• Código UNSPSC: 41115712
• NACRES: NB.21

Propiedades

• composición: bed wt, 100 mg
• envase: pk of 108
• técnicas: solid phase extraction (SPE): suitable
• volumen: 1 mL
• grupo activo de la matriz: WAX phase
• aplicaciones: food and beverages
• técnica de separación: ion exchange

Descripción

Descripción general

Retention Mechanism: Anion-exchange
Sample Matrix Compatibility: Organic or aqueous Solutions

• Weak anion exchanger ideal for extracting strong basic compounds that remain charged at all pH levels
• Unlike conventional weak anion exchange SPE phases such as -NH₂ (aminopropyl) that have a pKa of 9-10, a pH ≤ 7 is required to protonate or ionize the stationary phase to facilitate analyte retention. Elution is typically done by increasing the pH to 11 resulting in neutralization of the SPE phase.
• 2-(2-pyridyl)-ethyl silica gel has a pKa of ~6. Therefore, analyte elution is feasible at a pH ≥ 7. This characteristic is important for extracting analytes that are not stable (e.g. hydrolyzes) at high pHs typically required for elution when using traditional weak anion exchangers.
• Ideal for extracting acyl-coenzyme A esters from tissue.
• For more information, please see: Minkler, P.E., Kerner, J., Ingalls, S.T., Hoppel, C.L., Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue, Analytical Biochemistry 376 (2008) 275–276

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315,H319,H335
• Consejos de prudencia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable