11024AST

Astec^® CHIROBIOTIC^® V Chiral (5 μm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

• Sinónimos: V Chiral Stationary Phase Column
• Código UNSPSC: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Propiedades

• Nombre del producto: Astec^® Chirobiotic^® V Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
• Materiales: stainless steel column
• Nivel de calidad: 100
• Agency: suitable for USP L88
• descripción: HPLC Column
• Línea del producto: Astec^®
• envase: pkg of 1 ea
• fabricante / nombre comercial: Astec^®
• Parámetros: 0-45 °C temperature; 241 bar pressure (3500 psi)
• técnicas: HPLC: suitable; LC/MS: suitable
• L × D.I.: 25 cm × 4.6 mm
• Matriz: High-purity silica gel particle platform; fully porous particle
• grupo activo de la matriz: vancomycin phase
• tamaño de partícula: 5 μm
• tamaño de poro: 100 Å
• Intervalo de pH operativo: 3.5-7.0
• técnica de separación: chiral

Descripción

Descripción general

Neutral molecules, amides, acids, esters and amines show considerable enantioselectivity on these vancomycin-based CSPs. A wide variety of secondary and tertiary amines have been separated on the CHIROBIOTIC^® V in the polar ionic mode. The CHIROBIOTIC^® V has demonstrated many of the separation characteristics of protein-based stationary phases, but with exceptional stability and much higher sample capacity. Some chiral analytes have been resolved that have not been reported separated on any other chiral stationary phase. CHIROBIOTIC^® V and V2 differ in their bonding chemistry the pore size of the support particle, giving them different selectivity and preparative capacity.

• Bonded phase: Vancomycin
• Operating pH range: 3.5 - 7.0
• Particle diameter: 5, 10 or 16 μm
• Pore size: 100 Å (CHIROBIOTIC^® V) or 200 Å (CHIROBIOTIC^® V2)

Aplicación

Astec^® CHIROBIOTIC^® V Chiral HPLC column may be used for the separation of different types of racemic compounds (ß-blockers, ß-agonists, benzodiazipines, non-steroidal anti-inflammatory drugs, barbiturates, free and derivatized amino acids in packed column subcritical fluid chromatography (pSFC).[1] It may also be used for the separation of citalopram enantiomers and its two N-demethylated metabolites and of alprenolol that is the internal standard, in human plasma using chiral liquid chromatography.[2] It may also be used in the chiral liquid chromatography analysis of ketoprofen and flurbiprofen.[3]

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Información legal

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable