U9382
Ubiquitin-Carrier Protein H10 human
≥95% (SDS-PAGE), recombinant, expressed in E. coli (histidine-tagged), buffered aqueous glycerol solution
Sinónimos:
UbcH10
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Productos recomendados
biological source
human
Quality Level
recombinant
expressed in E. coli (histidine-tagged)
assay
≥95% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
~20 kDa
technique(s)
ligand binding assay: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... UBE2C(11065)
General description
Manufactured for Sigma by Boston Biochem., Inc.
Application
Ubiquitin-Carrier Protein H10 (UbcH10) human may be used to study the role of ubiquitin-proteasome system in pathogenesis of human diseases.
Biochem/physiol Actions
In conjunction with the anaphase-promoting complex, the protein catalyzes the destruction of both cyclin A and cyclin B.
Ubiquitin-Carrier Protein H10 human also referred to as UbcH10 is a recombinant protein that catalyzes the destruction of cyclin A as well as cyclin B along with the anaphase promoting complex and hence plays a pivotal role in controlling the cell exit from mitosis.
Physical form
Solution in 50 mM HEPES, pH 8.0, 125 mM NaCl, and 1 mM DTT in 10% glycerol.
wgk_germany
WGK 1
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
F M Townsley et al.
Proceedings of the National Academy of Sciences of the United States of America, 94(6), 2362-2367 (1997-03-18)
Destruction of mitotic cyclins by ubiquitin-dependent proteolysis is required for cells to complete mitosis and enter interphase of the next cell cycle. In clam eggs, this process is catalyzed by a cyclin-selective ubiquitin carrier protein, E2-C, and the cyclosome/anaphase promoting
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico