T8657

Trichloroacetic acid

suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), ≥99%

• Sinónimos: TCA
• Fórmula lineal: Cl₃CCOOH
• Número de CAS: 76-03-9
• Peso molecular: 163.39
• Beilstein/REAXYS Number: 970119
• EC Number: 200-927-2
• MDL number: MFCD00004177
• UNSPSC Code: 41105319
• PubChem Substance ID: 24900550
• NACRES: NB.22

Propiedades

• vapor density: <1 (vs air)
• vapor pressure: 1 mmHg ( 51 °C)
• assay: ≥99%
• form: powder or flakes (or crystals)
• technique(s): electrophoresis: suitable
• turbidity: ≤3 NTU (1 g/ml)
• refractive index: n20/D 1.62 (lit.)
• bp: 196 °C (lit.)
• mp: 54-58 °C (lit.)
• solubility: water: 1 g/mL, clear, colorless
• density: 1.62 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.001%; nitrate (NO₃^-): ≤0.002%; phosphate (PO₄^3-): ≤5 ppm; sulfate (SO₄^2-): ≤0.02%
• cation traces: Fe: ≤0.0005%; heavy metals (as Pb): ≤0.002%
• suitability: suitable for fixing solution (for IEF and PAGE gels)
• application(s): cell analysis
• storage temp.: 2-8°C
• SMILES string: OC(=O)C(Cl)(Cl)Cl
• InChI: 1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI key: YNJBWRMUSHSURL-UHFFFAOYSA-N

Descripción

General description

Trichloroacetic acid (TCA) is produced during the chlorination of water comprising natural organic material. It is a novel reagent used in clinical laboratories for deproteinization of body fluids. In addition, TCA is also used in the treatment of genital warts and acne scars.

Application

Trichloroacetic acid has been used:

• for hydrolysis of DNA isolated from the cell
• for precipitation of glutathione isolated from seminal plasma
• as a fixative in microscopy

Tradicionalmente usado para precipitar proteínas. Se ha utilizado para determinar la concentración de proteína por gravimetría. Usado como descalcificador y fijador en microscopía.

Información de seguridad

• pictograms: GHS05,GHS09
• signalword: Danger
• hcodes: H314,H410
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A
• Storage Class: 8B - Non-combustible corrosive hazardous materials
• wgk_germany: WGK 2
• flash_point_f: >235.4 °F - closed cup
• flash_point_c: > 113 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges