T7165
Tyrphostin 23
≥98%
Sinónimos:
(3,4-Dihydroxybenzylidene)malononitrile, RG-50810
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About This Item
Fórmula empírica (notación de Hill):
C10H6N2O2
Número de CAS:
Peso molecular:
186.17
Número MDL:
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
NACRES:
NA.77
Productos recomendados
origen biológico
synthetic (organic)
Ensayo
≥98%
Formulario
powder
potencia
35 μM IC50
solubilidad
DMSO: soluble 50 mg/mL, clear, yellow to brownish-yellow
temp. de almacenamiento
2-8°C
cadena SMILES
Oc1ccc(cc1O)\C=C(\C#N)C#N
InChI
1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H
Clave InChI
VTJXFTPMFYAJJU-UHFFFAOYSA-N
Información sobre el gen
human ... CDK2(1017)
Aplicación
Tyrphostin 23 can be used as a tyrosine kinase inhibitor for studying rat ghrelin-induced MAPK stimulation in GH3 cells. Tyrphostin 23 has also been used to analyze its effects on secretoneurin (SN)-induced chemotaxis of neutrophils.
Acciones bioquímicas o fisiológicas
Tyrphostin 23 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
Características y beneficios
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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