T5905
L-Thyronine
≥98.0% (TLC)
Sinónimos:
3-(p-[p-Hydroxyphenoxy]phenyl)-L-alanine
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About This Item
Fórmula empírica (notación de Hill):
C15H15NO4
Número de CAS:
Peso molecular:
273.28
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.26
Productos recomendados
Nombre del producto
L-Thyronine,
assay
≥98.0% (TLC)
Quality Level
form
powder
SMILES string
N[C@@H](Cc1ccc(Oc2ccc(O)cc2)cc1)C(O)=O
InChI
1S/C15H15NO4/c16-14(15(18)19)9-10-1-5-12(6-2-10)20-13-7-3-11(17)4-8-13/h1-8,14,17H,9,16H2,(H,18,19)/t14-/m0/s1
InChI key
KKCIOUWDFWQUBT-AWEZNQCLSA-N
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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J Köhrle
Cellular and molecular life sciences : CMLS, 57(13-14), 1853-1863 (2001-02-24)
Thyroid hormones control growth, development, differentiation and metabolism in vertebrates. Most of the actions of the active thyroid hormone T3 (3,5,3'-triiodo-L-thyronine) are exerted via ligand-activated nuclear T3 receptors. Activation of the secretory product of the thyroid gland, L-thyroxine (3,3',5,5'-tetraiodo-L-thyronine), or
J S LoPresti et al.
The Journal of clinical endocrinology and metabolism, 70(5), 1479-1484 (1990-05-01)
A hidden pool of rT3 production represents a source of rT3 that is minimally reflected in circulating rT3 levels. To test for the existence of such a source of rT3 production in man, varying doses of the generalized deiodinase inhibitor
I J Chopra et al.
The Journal of clinical endocrinology and metabolism, 75(1), 189-194 (1992-07-01)
A highly sensitive, specific, and reproducible RIA has been developed to measure T3 sulfate (T3S). Only T4 sulfate cross-reacted significantly (approximately 3%) in the RIA; rT3 sulfate, T4, T3, rT3, and diiodothyronine cross-reacted less than 0.01%. T3S was bound by
D B Ramsden et al.
Biomedical mass spectrometry, 11(4), 193-198 (1984-04-01)
The mass spectral properties of four classes of derivatives of thyronine are discussed ( oxazolidinone , O-methyl oxazolidinone , O-acetyl oxazolidinone and N,O- diheptafluorobutyryl methyl ester). An assay for thyronine in human urine is described based on the N,O- diheptafluorobutyryl
Kana Ohashi et al.
Biological & pharmaceutical bulletin, 44(2), 181-187 (2021-02-02)
Oligodendrocyte precursor cells (OPCs) are glial cells that differentiate into oligodendrocytes and myelinate axons. The number of OPCs is reportedly increased in brain lesions in some demyelinating diseases and during ischemia; however, these cells also secrete cytokines and elicit both
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