SRP6542

FNDC5

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• Sinónimos: Fibronectin Type III Domain-containing Protein 5, Fibronectin Type III Repeat-containing Protein 2
• UNSPSC Code: 12352202
• NACRES: NA.32

Propiedades

• recombinant: expressed in E. coli
• assay: ≥95% (SDS-PAGE)
• form: lyophilized
• mol wt: ~160 kDa
• packaging: pkg of 10 μg
• impurities: <0.1 EU/μg endotoxin (LAL test)
• UniProt accession no.: Q8NAU1
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... FNDC5(252995)

Descripción

General description

Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.

extracellular domain, human aa 32-152 / mouse aa 29-149 is untagged. FNDC5 extracellular domain has 100% identity between human, mouse and rat.

Physical form

Lyophilized in PBS.

Reconstitution

Reconstitute with 100 μsterile distilled water.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable