SRP4969

Epigen (EPGN) human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Sinónimos: ALGV3072, EPG, EPGN, Epigen, FLJ75542, PRO9904
• UNSPSC Code: 12352202
• NACRES: NA.32

Propiedades

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥98% (SDS-PAGE)
• form: lyophilized
• potency: 150-300 ng/mL
• mol wt: ~7.9 kDa
• packaging: pkg of 25 μg
• impurities: endotoxin, tested
• NCBI accession no.: Q6UW88
• UniProt accession no.: Q6UW88
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... EPGN(255324)

Descripción

General description

The precursor EPGN (epigen) is a transmembrane glycoprotein and is widely expressed in human tissues. The precursor is cleaved to give a soluble EGF (epidermal growth factor)-like domain.
Recombinant Human epigen, produced in Escherichia coli is a single, non-glycosylated, polypeptide chain containing 72 amino acids and having a molecular mass of 7.9kDa.

Biochem/physiol Actions

EPGN (epigen) is a ligand for EGFR (epidermal growth factor receptor). EPGN (epigen) belongs to the EGF family and enhances proliferation in keratinocytes.

Physical form

EPGN was lyophilized from 20 mM PBS buffer pH-7.4 containing 130 mM sodium chloride.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in sterile d-H₂O not less than 100 μg/ml. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA).