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SRP3104

Sigma-Aldrich

LD78 Beta Peptide

≥98% (HPLC), human recombinant, expressed in E. coli, suitable for cell culture

Sinónimos:

CCL3L1

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

product name

LD78 beta (CCL3L1) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

biological source

human

recombinant

expressed in E. coli

assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

mol wt

7.7 kDa

packaging

pkg of 20 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg endotoxin, tested

color

white to off-white

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CCL3L1(6349)

General description

LD78β is a CC chemokine that is closely related to MIP-1α. It signals through the CCR5 receptor and the beta-chemokine receptor, D6. LD78β has been shown to exhibit potent activity in HIV suppression assays. Recombinant human LD78β is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Biochem/physiol Actions

LD78b is a CC chemokine that is closely related to MIP-1a. It signals through the CCR5 receptor and the beta-chemokine receptor, D6. Recombinant human LD78b is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Sequence

APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA

Physical form

Lyophilized with no additives.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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M Nakao et al.
Molecular and cellular biology, 10(7), 3646-3658 (1990-07-01)
LD78 is a member of a newly identified superfamily of small inducible proteins involved in inflammatory responses, wound healing, and tumorigenesis. Southern blot analysis of the EcoRI-digested human genomic DNAs, using previously isolated LD78 cDNA as a probe, showed that

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