SML3476

Brivaracetam

≥98% (HPLC)

• Sinónimos: (αS,4R)-α-Ethyl-2-oxo-4-propyl-1-pyrrolidineacetamide, (2S)-2-[(4R)-2-Oxo-4-propylpyrrolidin-1-yl]butanamide, (S)-2-((R)-2-Oxo-4-propylpyrrolidin-1-yl)butanamide, UCB 34714, UCB-34714, UCB34714
• Fórmula empírica (notación de Hill): C₁₁H₂₀N₂O₂
• Número CAS: 357336-20-0
• Peso molecular: 212.29
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD25976668
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• drug control: USDEA Schedule V
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Descripción

Biochem/physiol Actions

Brivaracetam shows approximately 10 times greater potency than levetiracetam (Keppra)*; pIC50 at LBS = 7.0; inhibits audiogenic seizures in seizure-prone mice (ED50 = 14 μmol/kg) and is also effective in other animal models of epilepsy. Brivaracetam is used as an anticonvulsant (antiepileptic) for seizure treatment.

Orally active levetiracetam analog with higher synaptic vesicle protein 2A (SV2A) affinity and >10 times greater in vivo antiseizure efficay.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable