SML3334

Ceefourin 1

≥95% (HPLC)

• Sinónimos: 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione, Ceefourin-1
• Fórmula empírica (notación de Hill): C₁₁H₁₀N₄S₃
• Número CAS: 315702-40-0
• Peso molecular: 294.42
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD02329957
• Assay: ≥95% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: CN1C(CSC2=NC3=C(C=CC=C3)S2)=NNC1=S

Descripción

Biochem/physiol Actions

Ceefourin 1 is a potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor that exhibits low cellular toxicity and high microsomal and acid stability. Ceefourin 1 inhibits PDAC (pancreatic ductal adenocarcinoma) cell proliferation through MRP4-dependent cAMP extrusion thereby activation of the cAMP/Epac/Rap1 signaling pathway.

Potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable