SML3079

Ponalrestat

≥98% (HPLC)

• Sinónimos: 3-[(4-Bromo-2-fluorophenyl)methyl]-3,4-dihydro-4-oxo-1-phthalazineacetic acid, ICI 128436, MK538
• Fórmula empírica (notación de Hill): C₁₇H₁₂BrFN₂O₃
• Número CAS: 72702-95-5
• Peso molecular: 391.19
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00204117
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC(CC(C1=CC=CC=C1C2=O)=NN2CC3=CC=C(C=C3F)Br)=O
• InChI: 1S/C17H12BrFN2O3/c18-11-6-5-10(14(19)7-11)9-21-17(24)13-4-2-1-3-12(13)15(20-21)8-16(22)23/h1-7H,8-9H2,(H,22,23)
• InChI key: LKBFFDOJUKLQNY-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Ponalrestat is an orally available, potent and specific inhibitor of aldehyde reductase 2 (ALR2) that blocks the conversion of glucose to sorbitol. Ponalrestat promotes root elongation through the inhibition of the flavin monooxygenase YUCCA in Arabidopsis.

orally available, potent and specific inhibitor of aldehyde reductase 2 (ALR2)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable