SML2944
Mca-YVADAPK(Dnp)-OH trifluoroacetate
≥97% (HPLC)
Sinónimos:
Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp), TFA salt, Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH, TFA salt, Mca-YVADAPK(Dnp), TFA salt (Mca = 7-Methoxycoumarin-4-yl; Dnp = 2,4-dinitrophenyl)
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About This Item
Fórmula empírica (notación de Hill):
C53H64N10O19 · xC2HF3O2
Peso molecular:
1145.13 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
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Biochem/physiol Actions
Mca-YVADAPK(Dnp)-OH is a widely used fluorescent substrate for caspase-1 (ICE cleaves between D & A) and angiotensin-converting enzyme 2 (ACE2 cleaves between P & K). Proteolytic cleavage separates 7-methoxycoumarin-4-acetyl (Mca) from the fluorescence-quenching group 2,4-dinitrophenyl (Dnp), resulting in increased Mca fluorescence (Ex: 320-328 nm, Em: 405-420 nm).
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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