SML0765

SR1555

≥98% (HPLC)

• Sinónimos: 1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol
• Fórmula empírica (notación de Hill): C₂₂H₂₂F₆N₂O₂
• Número CAS: 1386439-51-5
• Peso molecular: 460.41
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL, clear
• storage temp.: 2-8°C

Descripción

Biochem/physiol Actions

SR1555 is a selective RORγ inverse agonist that inhibits the development and function of TH17 cells, a subset of T cells that have been implicated in the pathology of several autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. SR1555 also increases the frequency of T regulatory cells, an effect not seen with previously described RORγ ligands.

SR1555 is a selective RORγ inverse agonist.

Información de seguridad

• Códigos de peligro: H413
• Indicaciones de precaución: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable