SML0672

VU0405601

≥98% (HPLC)

• Sinónimos: 2-[(1-Bromo-2-naphthalenyl)oxy]-N-3-pyridinyl-acetamide
• Fórmula empírica (notación de Hill): C₁₇H₁₃BrN₂O₂
• Número CAS: 712325-30-9
• Peso molecular: 357.20
• NACRES: NA.77
• PubChem Substance ID: 329825580
• UNSPSC Code: 12352200
• MDL number: MFCD05995040
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: BrC1=C2C=CC=CC2=CC=C1OCC(NC3=CC=CN=C3)=O
• InChI: 1S/C17H13BrN2O2/c18-17-14-6-2-1-4-12(14)7-8-15(17)22-11-16(21)20-13-5-3-9-19-10-13/h1-10H,11H2,(H,20,21)
• InChI key: WLLRAGBPCSOJNH-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

VU0405601 is a hERG (the human Ether-à-go-go-Related Gene) agonist that increased the IC₅₀ of dofetilide from 38.7 nM to 76.3 nM. VU0405601 protects against arrhythmias induced by hERG inhibition.

VU0405601 is a hERG agonist that protects against arrhythmias induced by hERG inhibition.

Información de seguridad

• Pictogramas: GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H302,H315,H319,H335
• Indicaciones de precaución: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos diana: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable