SML0377

(S)-FTY720 phosphate

≥94% (HPLC)

• Sinónimos: (+)-(S)-FTY 720 phosphate, (2S)-2-Amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol), (S)-FTY 720P
• Fórmula empírica (notación de Hill): C₁₉H₃₄NO₅P
• Número de CAS: 402616-26-6
• Peso molecular: 387.45
• UNSPSC Code: 12352211

Propiedades

• assay: ≥94% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 0.3 mg/mL, clear (warmed)
• storage temp.: −20°C

Descripción

Biochem/physiol Actions

FTY20 phosphate (FTY720-P) is a sphingosine 1-phosphate (S1PR) receptor agonist and immunomodulatory agent, the active metabolite of FTY720. FTY720P acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5), with IC₅₀ values of 0.2-6 nM.

Features and Benefits

This compound is featured on the Lysophospholipid Receptors and Lysophospholipid Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable