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SCP0249

Sigma-Aldrich

Pancreatic Elastase substrate

≥95% (HPLC), lyophilized

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5 MG
$205.00

$205.00

Normalmente se envía en 2 semanas.
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$205.00

About This Item

Fórmula empírica (notación de Hill):
C32H43N5O8
Peso molecular:
625.71
Código UNSPSC:
12352200
NACRES:
NA.32

$205.00

Normalmente se envía en 2 semanas.

Nombre del producto

Pancreatic Elastase substrate,

Ensayo

≥95% (HPLC)

Formulario

lyophilized

composición

Peptide Content, ≥85%

condiciones de almacenamiento

protect from light

temp. de almacenamiento

−20°C

Amino Acid Sequence

MeOSuc-Ala-Ala-Pro-Val-4-MNA

Aplicación

Elastase(s) can be assayed and differentiated using chromogenic and fluorogenic Pro-Val peptide substrates such as Glp-Pro-Val-pNA and MeOSuc-Ala-Ala-Pro-Val-4-MNA.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
23971
LK0188

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Pier Carlo Braga et al.
Pharmacology, 77(3), 150-154 (2006-07-11)
Erdosteine is a mucolytic drug whose metabolization gives rise to an active metabolite with an SH group (Met I), which reduces neutrophil release of reactive oxygen species and the peroxynitrite generated by the reaction of superoxide anion with nitric oxide
H Moriuchi et al.
Intensive care medicine, 24(7), 709-715 (1998-08-29)
Oleic acid (OA) can produce a lung injury similar to the adult respiratory distress syndrome (ARDS). Elastase and superoxides are thought to have an effect in ARDS. However, the effect that elastase and superoxide have in OA lung injury is
J V Edwards et al.
The journal of peptide research : official journal of the American Peptide Society, 66(4), 160-168 (2005-09-06)
An assessment of elastase-substrate kinetics and adsorption at the solid-liquid interface of peptide-bound resin was made in an approach to the solid-phase detection of human neutrophil elastase (HNE), which is found in high concentration in chronic wound fluid. N-succinyl-alanine-alanine-proline-valine-p-nitroanilide (suc-Ala-Ala-Pro-Val-pNA)
D Nunley et al.
American journal of respiratory and critical care medicine, 159(1), 258-261 (1999-01-05)
Large numbers of neutrophils with unopposed neutrophil elastase (NE) proteolytic activity are found in lower respiratory tract secretions from most patients with advanced cystic fibrosis (CF). To determine whether antielastase defenses may be overwhelmed in epithelial lining fluid after lung
G Dent et al.
Lung, 173(3), 165-175 (1995-01-01)
Elastase and antielastase activities were measured in bronchoalveolar lavage fluid (BALF) and their relationship to bronchoalveolar lavage (BAL) neutrophil numbers was assessed in order to determine whether the elevated BAL neutrophil count can predict a shift in the elastase/antielastase balance.
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Questions

1–2 of 2 Questions  

  1. What is the maximum excitation and emission wavelength for Product SCP0249, Pancreatic Elastase substrate?

    1 answer

    1. The excitation wavelength for Product SCP0249, Pancreatic Elastase substrate is 335-350 nm and the emission wavelength is 410-440 nm.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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