SCP0117
Cionin Peptide
≥95% (HPLC), lyophilized powder
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About This Item
Fórmula empírica (notación de Hill):
C53H63N11O19S3
Peso molecular:
1254.32
UNSPSC Code:
12352202
NACRES:
NA.32
Productos recomendados
product name
Cionin,
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥85%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Asn-Tyr(SO3H)-Tyr(SO3H)-Gly-Trp-Met-Asp-Phe-NH2
Application
Protochordean octapeptide cionin is a structural hybrid of mammalian cholecystokinin (CCK) and gastrin with functions most similar to those of CCK. Cionin is used as a potent and efficient stimulator of gastric histamine release and acid secretion via a CCK-B receptor.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
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Tsuyoshi Kawada et al.
Zoological science, 27(2), 134-153 (2010-02-10)
The critical phylogenetic position of ascidians leads to the presumption that neuropeptides and hormones in vertebrates are highly likely to be evolutionarily conserved in ascidians, and the cosmopolitan species Ciona intestinalis is expected to be an excellent deuterostome Invertebrate model
B Schjoldager et al.
The American journal of physiology, 260(6 Pt 1), G976-G982 (1991-06-01)
The protochordean octapeptide cionin is structurally a hybrid of mammalian cholecystokinin (CCK) and gastrin, and thus their possible common ancestor. To determine whether cionin behaves like CCK or gastrin, we examined its effect on canine fundic somatostatin cells and on
Stimulation by the ancestral member of the CCK/gastrin family, cionin, of trout gallbladder contraction.
A H Johnsen et al.
Annals of the New York Academy of Sciences, 713, 404-406 (1994-03-23)
R Mårvik et al.
Scandinavian journal of gastroenterology, 29(7), 591-594 (1994-07-01)
The protochordean octapeptide cionin is structurally a hybrid of mammalian cholecystokinin (CCK) and gastrin. An earlier study has shown that cionin in mammals stimulates gallbladder contraction and gastric somatostatin release, similarly to CCK-8. In the present study we examined the
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