The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Inmunógeno
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human XRCC1 (P18887).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Aplicación
WB
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
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Certificados de análisis (COA)
Lot/Batch Number
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