SAB5201187

Monoclonal Anti-Lrrk2/Dardarin - Biotin antibody produced in mouse

clone S231B-34, purified immunoglobulin

• Sinónimos: Anti-Dardarin, Anti-Leucine-rich repeat kinase 2, Anti-PARK8, Anti-RIP7
• UNSPSC Code: 12352203
• NACRES: NA.41
• conjugate: biotin conjugate
• application: ICC; IHC; WB
• clone: S231B-34, monoclonal
• species reactivity: human, rat
• citations: 3
• technique(s): immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable

Propiedades

• biological source: mouse
• Quality Level: 100
• conjugate: biotin conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: S231B-34, monoclonal
• form: buffered aqueous solution
• mol wt: antigen predicted mol wt 200 kDa
• species reactivity: human, rat
• concentration: 1 mg/mL
• technique(s): immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• isotype: IgG2a
• NCBI accession no.: NP_940980
• UniProt accession no.: Q5S007
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... LRRK2(120892)

Descripción

General description

Leucine rich repeat kinase 2 (LRRK2) is a large protein containing protein-protein interaction region enclosing two main domains for : central kinase and GTPase.

Immunogen

Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat. <30% identity with LRRK1.

Biochem/physiol Actions

Mutation in the leucine rich repeat kinase 2 (LRRK2) gene causes familial Parkinson′s disease (PD) and sporadic PD. Mitochondrial dysfunction is observed as a result of LRRK2 gene variation.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

PBS pH 7.4, 50% glycerol, 0.1% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable