S7448

STF-62247

≥98% (HPLC), solid

• Sinónimos: N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine
• Fórmula empírica (notación de Hill): C₁₅H₁₃N₃S
• Número CAS: 315702-99-9
• Peso molecular: 267.35
• NACRES: NA.77
• PubChem Substance ID: 329824583
• UNSPSC Code: 12352200
• MDL number: MFCD01121974
• Assay: ≥98% (HPLC)
• Form: solid

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• solubility: DMSO: soluble 26 mg/mL, H₂O: insoluble
• storage temp.: room temp
• SMILES string: Cc1cccc(Nc2nc(cs2)-c3ccncc3)c1
• InChI: 1S/C15H13N3S/c1-11-3-2-4-13(9-11)17-15-18-14(10-19-15)12-5-7-16-8-6-12/h2-10H,1H3,(H,17,18)
• InChI key: KATNUHQNJGNLPW-UHFFFAOYSA-N

Descripción

Application

STF-62247 may be used as positive control in autophagy inducing cell signaling studies.

Biochem/physiol Actions

STF-62247 induces the formation of large vacuoles in the von Hippel-Lindau deficient renal carcinoma cells, a characteristic of autophagy.¹

STF-62247 is a selective inducer of autophagy in VHL-deficient renal cell carcinoma cells.

Información de seguridad

• hcodes: H413
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 2
• ppe: dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges