Saltar al contenido
MilliporeSigma
Todas las fotos(2)

Documentos

P9879

Sigma-Aldrich

Procaine hydrochloride

≥97% (HPLC), powder, Na⁺ channel blocker

Sinónimos:

4-Aminobenzoic acid 2-diethylaminoethyl ester, p-Aminobenzoic acid diethylaminoethyl ester hydrochloride, Novocaine hydrochloride

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(2)

About This Item

Fórmula lineal:
H2NC6H4CO2CH2CH2N(C2H5)2·HCl
Número de CAS:
51-05-8
Peso molecular:
272.77
Beilstein/REAXYS Number:
3917802
EC Number:
200-077-2
MDL number:
MFCD00013000
UNSPSC Code:
12352200
PubChem Substance ID:
24278665
NACRES:
NA.77

product name

Procaine hydrochloride, ≥97%

assay

≥97%

form

powder

mp

155-156 °C (lit.)

originator

Celgene

SMILES string

Cl.CCN(CC)CCOC(=O)c1ccc(N)cc1

InChI

1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H

InChI key

HCBIBCJNVBAKAB-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

Procaine hydrochloride has been used as a component of Krebs Henseleit buffer for incubating the left ventricular cardiac tissue in its resting length. It has also been used as an inducer in M9 media for induction assay.

Biochem/physiol Actions

Procaine is a Na+ channel blocker, commonly used as an anesthetic agent and is considered safer than cocaine. It is also useful as a painkiller to treat pain, associated with joints and tendons.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Celgene. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H317

Hazard Classifications

Acute Tox. 3 Oral - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Ophthalmic Anaesthesia, 5-5 (2002)
Equine Anesthesia E-Book: Monitoring and Emergency Therapy, 215-215 (2002)
J Dudel et al.
Journal of neurophysiology, 81(5), 2386-2397 (1999-05-13)
of quantal end-plate currents of mouse muscle by physostigmine and procaine. Quantal endplate currents (qEPCs) were recorded from hemidiaphragms of mice by means of a macro-patch-clamp electrode. Excitation was blocked with tetrodotoxin, and quantal release was elicited by depolarizing pulses
Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation
Axelsen LN, et al.
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 298(6), R1560-R1570 (2010)
Phillippe P Gonzalez et al.
Glia, 66(5), 999-1015 (2018-02-03)
Malignant glioma is one of the deadliest types of cancer. Understanding how the cell of origin progressively evolves toward malignancy in greater detail could provide mechanistic insights and lead to novel concepts for tumor prevention and therapy. Previously we have
Ver todos los artículos relacionados

Artículos

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico