The product is tested for solubility at 50 mg/ml in water. This information can be found in the specification sheet or Certificate of Analysis accessible from the Product Detail Page.
P6126
(R)-(−)-Phenylephrine hydrochloride
≥99% (titration), powder, α₁-adrenoceptor agonist
Sinónimos:
(R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Seleccione un Tamaño
5 G
$62.20
10 G
$120.00
25 G
$236.55
50 G
$391.00
100 G
$547.00
Seleccione un Tamaño
Cambiar Vistas
5 G
$62.20
10 G
$120.00
25 G
$236.55
50 G
$391.00
100 G
$547.00
About This Item
Fórmula lineal:
HOC6H4CH(CH2NHCH3)OH·HCl
Número de CAS:
Peso molecular:
203.67
Beilstein/REAXYS Number:
4158948
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Productos recomendados
Nombre del producto
(R)-(−)-Phenylephrine hydrochloride, powder
form
powder
Quality Level
mp
143-145 °C (lit.)
originator
Johnson & Johnson
SMILES string
OC1=CC([C@H](CNC)O)=CC=C1.Cl
InChI
1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1
InChI key
OCYSGIYOVXAGKQ-FVGYRXGTSA-N
Gene Information
human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)
¿Está buscando productos similares? Visita Guía de comparación de productos
General description
(R)-(-)-Phenylephrine hydrochloride is an adrenergic agent, which functions as a β-receptor sympathomimetic drug.[1]
Application
(R)-(-)-Phenylephrine hydrochloride has been used:
- in the preparation and culturing of cardiocytes and fibroblasts[2]
- to stimulate myocardial strips to measure slice contraction[3]
- in primary cardiomyocyte culture to show the effect of Kruppel-like factors (KLF) on cardiac hypertrophy in vivo[4]
- to evaluate the pharmacological response of embryonic stem cell (ESC)-derived cardiomyocytes[5]
- to pharmacologically rescue GATA (erythroid transcription factor) binding protein 3 (GATA3) null embryo from early embryonic lethality[6]
Biochem/physiol Actions
α1-adrenoceptor agonist.
Features and Benefits
This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1B
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Elija entre una de las versiones más recientes:
Certificados de análisis (COA)
Lot/Batch Number
¿No ve la versión correcta?
Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Los clientes también vieron
Effect of basic fibroblast growth factor on cardiomyocyte differentiation from mouse embryonic stem cells.
Khezri S, et al.
Saudi Medical Journal, 28(2), 181-186 (2007)
A myocardial slice culture model reveals alpha-1A-adrenergic receptor signaling in the human heart
Thomas RC, et al.
JACC. Basic to translational science, 1(3), 155-167 (2016)
Clenbuterol induces cardiac myocyte hypertrophy via paracrine signalling and fibroblast-derived IGF-1
Bhavsar PK, et al.
Journal of Cardiovascular Translational Research, 3(6), 688-695 (2010)
Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3
Udager AM, et al.
Gastroenterology, 146(1), 157-165 (2014)
Kruppel-like factor 4 regulates pressure-induced cardiac hypertrophy
Liao X, et al.
Journal of Molecular and Cellular Cardiology, 49(2), 334-338 (2010)
Artículos
Review alpha 1 adrenoceptors as well as their agonists, antagonists, and tissue expression patterns. We suggest several modulators and alternatives for working with a-1 adrenoreceptors.
Chromatograms
application for HPLC-
How to dissolve the power of PE.
1 answer-
Helpful?
-
-
Is (R)-(-)-Phenylephrine hydrochloride the same as L-Phenylephrine hydrochloride?
1 answer-
(R)-(-)-Phenylephrine hydrochloride is also named l-Phenylephrine hydrochloride (lower case el) or Levophenylephrine hydrochloride.
Helpful?
-
-
What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Helpful?
-
Active Filters
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico
