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MilliporeSigma

P5289

Sigma-Aldrich

Anti-Progesterone antibody produced in rabbit

whole antiserum, lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
51111800
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

radioimmunoassay: suitable (dextran coated charcoal 3H RIA)

UniProt accession no.

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... PGR(5241)

Immunogen

progesterone-11α-BSA.

Application

Anti-Progesterone antibody produced in rabbit has been used in enzyme linked immunosorbent assay (ELISA) and competitive binding assay.

Biochem/physiol Actions

Progesterone or P4 (pregn-4-ene-3,20-dione) is a female steroid hormone that belongs to the hormones class, progestogens. It is produced by majorly by ovaries, adrenal glands and placenta of humans and other species. Progesterone derived from placenta and corpus luteum is required for the maintenance of pregnancy. Progesterone inhibits the T cell mediated immune response involved in tissue rejection. The progesterone levels in females are low before ovulation and are elevated during the luteal phase.

Reconstitution

Reconstitute with 5 mL buffer: 0.05 M Tris-HCl, pH 8.0, 0.1 M sodium chloride, 0.1% gelatin and 15 mM sodium azide. Store this stock at −20 °C. Working dilution (1:10) to be discarded if unused within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Shuzhi Zhou et al.
The Journal of comparative neurology, 521(13), 3003-3029 (2013-03-19)
In naked mole-rat (NMR) colonies, breeding is monopolized by the queen and her consorts. Subordinates experience gonadal development if separated from the queen. To elucidate the neuroendocrine factors underlying reproductive suppression/development in NMRs, we quantified plasma gonadal steroids and GnRH-1-
Socially regulated reproductive development: Analysis of GnRH-1 and kisspeptin neuronal systems in cooperatively breeding naked mole-rats (Heterocephalus glaber)
Zhou S, et al.
The Journal of Comparative Neurology, 521(13), 3003-3029 (2013)
Steroids.
N Applezweig
Chemical week, 104, 57-72 (1969-05-17)
Prostaglandin F2alpha induces expression of activating transcription factor 3 (ATF3) and activates MAPK signaling in the rat corpus luteum
Guo N, et al.
Acta Histochemica, 117(2), 211-218 (2015)
Progesterone and maintenance of pregnancy: is progesterone nature's immunosuppressant?
P K Siiteri et al.
Annals of the New York Academy of Sciences, 286, 384-397 (1977-03-11)

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