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P0100

Sigma-Aldrich

Psilocybin

≥98% (HPLC), solid

Sinónimos:

3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl phosphate

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About This Item

Fórmula empírica (notación de Hill):
C12H17N2O4P
Número de CAS:
520-52-5
Peso molecular:
284.25
EC Number:
208-294-4
MDL number:
MFCD01310431
UNSPSC Code:
12352200
NACRES:
NA.77

assay

≥98% (HPLC)

form

solid

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

H2O: >20 mg/mL

storage temp.

−20°C

SMILES string

CN(C)CCc1c[nH]c2cccc(OP(O)(O)=O)c12

Biochem/physiol Actions

Psilocybin is a hallucinogenic serotonin 1A and 2A agonist and psychotomimetic.
Psilocybin is a hallucinogenic serotonin 1A and 2A agonist and psychotomimetic. It is the minor hallucinogenic component of Teonanácatl, the sacred mushroom of Mexico. Psilocybin produces muscle relaxation, dilation of pupils, vivid visual and auditory distortions, and emotional disturbances.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
127K4703

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Michael Kometer et al.
Biological psychiatry, 72(11), 898-906 (2012-05-15)
Serotonin (5-HT) 1A and 2A receptors have been associated with dysfunctional emotional processing biases in mood disorders. These receptors further predominantly mediate the subjective and behavioral effects of psilocybin and might be important for its recently suggested antidepressive effects. However
Matthew W Johnson et al.
Drug and alcohol dependence, 123(1-3), 132-140 (2011-12-02)
Psilocybin is a well-characterized classic hallucinogen (psychedelic) with a long history of religious use by indigenous cultures, and nonmedical use in modern societies. Although psilocybin is structurally related to migraine medications, and case studies suggest that psilocybin may be efficacious
Robin L Carhart-Harris et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(6), 2138-2143 (2012-02-07)
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here we used psilocybin, a classic psychedelic found
Opening doors of perception: psychedelic drugs and end-of-life care.
Norra Macready
Journal of the National Cancer Institute, 104(21), 1619-1620 (2012-10-30)
Hallucinogen actions on human brain revealed.
Hyeong-Min Lee et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(6), 1820-1821 (2012-02-07)
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