P0064

PalGly

≥98% (HPLC), solid

• Sinónimos: N-(1-Oxohexadecyl)glycine, N-Hexadecanoylglycine, Hexadecanoylaminoacetic acid, N-palmitoyl glycine
• Fórmula empírica (notación de Hill): C₁₈H₃₅NO₃
• Número CAS: 2441-41-0
• Peso molecular: 313.48
• NACRES: NA.77
• PubChem Substance ID: 329820003
• UNSPSC Code: 12352200
• MDL number: MFCD00153471
• Assay: ≥98% (HPLC)
• Form: solid

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white to off-white
• solubility: DMSO: >10 mg/mL
• storage temp.: 2-8°C
• SMILES string: O=C(CCCCCCCCCCCCCCC)NCC(O)=O
• InChI: 1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)
• InChI key: KVTFEOAKFFQCCX-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production.

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.

Features and Benefits

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)