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O9505

Sigma-Aldrich

Orotidine

≥90% (HPLC)

Sinónimos:

Uridine-6-carboxylic acid

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About This Item

Fórmula empírica (notación de Hill):
C10H12N2O8
Número de CAS:
314-50-1
Peso molecular:
288.21
MDL number:
MFCD00057418
UNSPSC Code:
41106305
PubChem Substance ID:
329818941

assay

≥90% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C(=O)NC(=O)C=C2C(O)=O

InChI

1S/C10H12N2O8/c13-2-4-6(15)7(16)8(20-4)12-3(9(17)18)1-5(14)11-10(12)19/h1,4,6-8,13,15-16H,2H2,(H,17,18)(H,11,14,19)/t4-,6-,7-,8-/m1/s1

InChI key

FKCRAVPPBFWEJD-XVFCMESISA-N

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Application

Orotidine, a nucleoside found naturally in fungi, bacteria and plants, may be used as a reference for the determination of presence of orotidine in urine or plasma due to urea cycle-related (transamidation) metabolic deficiencies or diseases.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
048H5860
041K7017
115H7819
091H7860
076H7857

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H Horiuchi et al.
Life sciences, 66(21), 2051-2070 (2000-05-24)
We investigated the relationship between the toxic effect of allopurinol and pyrimidine metabolism in mice. Allopurinol-induced increases in plasma transaminase levels in dinitrofluorobenzene (DNFB)-sensitized mice were not affected by uridine. In contrast, plasma creatinine and BUN tended to decrease 18
A B Burlina et al.
Journal of inherited metabolic disease, 15(5), 707-712 (1992-01-01)
The allopurinol challenge test was performed on 44 healthy subjects (28 children and 16 adolescents) in order to establish normal values of urinary orotic acid excretion following allopurinol ingestion in the paediatric population. The subjects were divided into three groups
Elizabeth M Brown et al.
PloS one, 8(3), e59237-e59237 (2013-03-28)
Analysis of the population genetic structure of microbial species is of fundamental importance to many scientific disciplines because it can identify cryptic species, reveal reproductive mode, and elucidate processes that contribute to pathogen evolution. Here, we examined the population genetic
K J Kwon-Chung et al.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 30(1), 61-69 (1992-01-01)
Spontaneous mutants requiring uracil were isolated from both varieties of Cryptococcus neoformans by plating on 5-fluoroorotic acid (5-FOA) medium. Of the 36 strains tested (18 var. neoformans and 18 var. gattii), 24 (12 of each variety) generated 5-FOA-resistant cells requiring
J A Arranz et al.
Clinical chemistry, 45(7), 995-1001 (1999-07-01)
The diagnosis of heterozygosity for X-linked ornithine carbamoyltransferase (OCT) deficiency has usually been based on measurement of the increase of orotate and orotidine excretion after an allopurinol load. We examined the choices of analyte, cutoff, and test conditions to obtain
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