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MAK065

Sigma-Aldrich

Lactate Assay Kit II

sufficient for 100 colorimetric tests

Sinónimos:

Lactic Acid Assay Kit

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84

usage

sufficient for 100 colorimetric tests

application(s)

cosmetics
food and beverages

detection method

colorimetric

relevant disease(s)

endocrinological disorders, diabetes; cancer

storage temp.

−20°C

General description

L(+)-Lactate is a metabolic compound formed in animals by the action of the enzyme Lactate Dehydrogenase. Lactate is produced in proliferating cells and during anaerobic conditions such as exercise. Abnormally high concentrations of lactate have been related to pathological conditions such as cancer, diabetes, and lactate acidosis. L(+)-Lactate is the major stereoisomer of lactate formed in human intermediary metabolism and is present in blood at levels of around 1-2 mmol/L. This kit provides a convenient means for detecting L(+)-Lactate in biological samples.

Application

Lactate Assay Kit II has been used to measure the levels of lactate in samples.

Suitability

Suitable for detecting L(+)-Lactate in culture medium, fermentation medium, blood and cells.

Principle

Lactate concentration is determined by an enzyme assay, which results in a colorimetric (450 nm) product, proportional t the lactate present. There is no need of pretreatment or purification of samples. Typical sensitivities of detection are between 0.02-10 mM of lactate.

replaced by

Referencia del producto
Descripción
Precios

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Our knowledge of how genetic risk variants contribute to psychiatric disease is mainly limited to neurons. However, the mechanisms whereby the same genetic risk factors could affect the physiology of glial cells remain poorly understood. We studied the role of
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McAnulty M J, et al.
Biotechnology and Bioengineering, 114(4), 852-861 (2017)
DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders.
Jouroukhin Y, et al.
Translational Psychiatry, 8(1), 76-76 (2018)
Camaron R Hole et al.
Nature communications, 10(1), 2955-2955 (2019-07-06)
Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack antigen specificity and be devoid of immunological memory. Strategies that can induce memory-like responses from innate cells can be utilized to elicit protective immunity in
Nicole J Van Bergen et al.
PloS one, 10(10), e0140919-e0140919 (2015-10-27)
Primary Open Angle Glaucoma (POAG) is a common neurodegenerative disease characterized by the selective and gradual loss of retinal ganglion cells (RGCs). Aging and increased intraocular pressure (IOP) are glaucoma risk factors; nevertheless patients deteriorate at all levels of IOP
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