M7769
IgG2a, Kappa from murine myeloma
clone UPC 10, ascites fluid, lyophilized powder
Sinónimos:
Mouse IgG2a-κ
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5 MG
$383.57
5 X 5 MG
$1,360.00
$383.57
Precio de catálogo$412.00Ahorre 7 %Disponible para envío el02 de abril de 2025Detalles
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5 MG
$383.57
5 X 5 MG
$1,360.00
About This Item
$383.57
Precio de catálogo$412.00Ahorre 7 %Disponible para envío el02 de abril de 2025Detalles
Solicitar un pedido a granel
Productos recomendados
origen biológico
mouse
Nivel de calidad
conjugado
unconjugated
forma del anticuerpo
ascites fluid
clon
UPC 10, monoclonal
Formulario
lyophilized powder
temp. de almacenamiento
2-8°C
modificación del objetivo postraduccional
unmodified
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Descripción general
The UPC-10 tumor line that produces mouse IgG2a, K is a tetramethylpentadecane (pristane) induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. The hapten binding specificity of the UPC-10 line is for β-2-6-linked fructosan. The ascites produced from the UPC-10 tumor line contains IgG2a, K in addition to normal levels of other mouse immunoglobulins and serum proteins. The ascites fluid is clarified by centrifugation and filtration. IgG2a (immunoglobulin G 2a) is one of the subclasses of rat immunoglobulins, which also include IgG1, IgG2b and IgG2c.[1]
Especificidad
Antigen Specificity: β-2,6-fructosan
Trace amounts of lambda chain may be present.
Trace amounts of lambda chain may be present.
Inmunógeno
The UPC-10 tumor line that produces mouse IgG2a, K is a tetramethylpentadecane (pristane) induced plasmacytoma originated and carried intraperitoneally in BALB/c mice.
Aplicación
Acciones bioquímicas o fisiológicas
The IgG2a (immunoglobulin G 2a) plays a vital role in stimulating autoimmunity in mice. This gene is expressed at high level during virus infection.[4] IgG2a offers host defence through activation of complement system. This antibody has specificity towards Fc receptors expressed on phagocytes and stimulates antibody-dependent cell mediated cytotoxicity.[5] IgG2a also induces macrophage-mediated opsonophagocytosis, which has been observed in response to influenza virus and leads to its clearance from the infected cells.[6]
Forma física
The product provided is lyophilized from 0.01 M phosphate buffered saline, pH 7.2, with no preservatives added.
Nota de preparación
Storage and Stability: Store the product at 2-8 °C. After reconstitution, the solution may be stored frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage clarify the solution by centrifugation before use.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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