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M5634

Sigma-Aldrich

5-Mercuricytidine carbonate 5′-triphosphate triethylammonium salt

~90%

Sinónimos:

Hg-CTP

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About This Item

Fórmula lineal:
C9H15HgN3O14P3 · HCO3
Número de CAS:
100940-62-3
Peso molecular:
1148.52
MDL number:
MFCD00058366
UNSPSC Code:
41106305
PubChem Substance ID:
329818019
NACRES:
NA.51

assay

~90%

form

solid

storage temp.

−20°C

SMILES string

CCN(CC)CC.NC1=NC(=O)N(C=C1[Hg])[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O

InChI

1S/C9H15N3O14P3.C6H15N.Hg/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;1-4-7(5-2)6-3;/h2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);4-6H2,1-3H3;/t4-,6-,7-,8-;;/m1../s1

InChI key

CKMVNPSLWQKVPG-WFIJOQBCSA-N

Application

5-Mercuricytidine carbonate 5;-triphosphate (Hg-CTP) may be used as a substrate to generate mercurated DNA that may be suitable for image based DNA sequencing strategies.

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análisis (COA)

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Study of deoxyribonucleic acid replication in permeable cells of Bacillus subtilis using mercurated nucleotide substrates.
S Bhattacharya et al.
Biochemistry, 20(11), 3029-3034 (1981-05-26)
G Banfalvi et al.
Analytical biochemistry, 146(1), 64-70 (1985-04-01)
A method for isolating picomole quantities of nascent mercurated DNA from a mixture of cellular nucleic acids using affinity chromatography on thiol-agarose is described. Analysis of mercurated DNA (HgDNA) isolated in the presence of in vivo-labeled cellular RNA or in
R M Dale et al.
Proceedings of the National Academy of Sciences of the United States of America, 70(8), 2238-2242 (1973-08-01)
A simple acetoxymercuration reaction for introducing covalently bound mercury atoms into nucleotides is described. The 5-mercuriacetate derivatives of UTP, CTP, dUTP, and dCTP, as well as the 7-mercuriacetate derivative of 7-deazaATP, have been prepared by this procedure and tested as
S Bhattacharya et al.
The Journal of biological chemistry, 257(4), 1610-1612 (1982-02-25)
Mercurated DNA was synthesized in permeable cells of Bacillus subtilis, using 5-mercurideoxycytidine triphosphate as one of the substrates, and was separated from parental unsubstituted DNA by isopycnic centrifugation in CsCl gradients. The ability of mercurated DNA to transform auxotrophic strains
Structural analyses on the mercury(II)-mediated T-T base pair.
Tanaka Y, Oda S, et al.
Nucleic Acids Symposium Series, 50, 47-48 (2006)
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