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MilliporeSigma

M3655

Sigma-Aldrich

D-Mannose 6-phosphate sodium salt

≥98% (HPLC)

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$255.00
1 G
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Disponible para envío el31 de marzo de 2025Detalles


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100 MG
$255.00
1 G
$1,260.00

About This Item

Fórmula lineal:
C6H12O9PNa
Número de CAS:
Peso molecular:
282.12
Número MDL:
Código UNSPSC:
12352201
ID de la sustancia en PubChem:
NACRES:
NA.25

$255.00


Disponible para envío el31 de marzo de 2025Detalles


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origen biológico

synthetic (inorganic)

Ensayo

≥98% (HPLC)

Formulario

powder

técnicas

HPLC: suitable

impurezas

<12% water (Karl Fischer)

color

white

solubilidad

water: 50 mg/mL, clear to cloudy, colorless

trazas de catión

Na: 7.3-9.0% (anhydrous)

temp. de almacenamiento

2-8°C

cadena SMILES

[Na].OC(COP(O)(O)=O)C(O)C(O)C(O)C=O

InChI

1S/C6H13O9P.Na.H/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14;;/h1,3-6,8-11H,2H2,(H2,12,13,14);;

Clave InChI

RUFPTDNHMAGVMV-UHFFFAOYSA-N

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Descripción general

Mannose is a monosaccharide.

Aplicación

Mannose has been used in a study to assess in vivo targeting of alveolar macrophages. [1] It has also been used in a study to investigate genetic engineering of the phosphocarrier protein NPr. [2]

Acciones bioquímicas o fisiológicas

Mannose-6-Pis a molecule bound by lectin in the immune system. It is converted to fructose 6-phosphate by mannose phosphate isomerase and is a key targeting signal for acid hydrolase precursor proteins that are transported to lysosomes.

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Yossef Lopez-de Los Santos et al.
The Journal of biological chemistry, 287(35), 29931-29939 (2012-07-07)
The Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system (PTS) in prokaryotes mediates the uptake and phosphorylation of its numerous substrates through a phosphoryl transfer chain where a phosphoryl transfer protein, HPr, transfers its phosphoryl group to any of several sugar-specific Enzyme IIA
Petra Tiels et al.
Nature biotechnology, 30(12), 1225-1231 (2012-11-20)
Lysosomal storage diseases are treated with human lysosomal enzymes produced in mammalian cells. Such enzyme therapeutics contain relatively low levels of mannose-6-phosphate, which is required to target them to the lysosomes of patient cells. Here we describe a method for
Wei Cheong Ngeow et al.
Journal of anatomy, 219(5), 638-645 (2011-08-05)
Microsurgical repair of transected peripheral nerves is compromised by the formation of scar tissue and the development of a neuroma, thereby limiting the success of regeneration. The aim of this study was to quantify histomorphometrically the structural changes in neural
C Henrique Serezani et al.
Journal of immunology (Baltimore, Md. : 1950), 189(2), 906-915 (2012-06-15)
Pattern recognition receptors for fungi include dectin-1 and mannose receptor, and these mediate phagocytosis, as well as production of cytokines, reactive oxygen species, and the lipid mediator leukotriene B(4) (LTB(4)). The influence of G protein-coupled receptor ligands such as LTB(4)
Xuezheng Song et al.
Methods in molecular biology (Clifton, N.J.), 808, 137-148 (2011-11-08)
Glycan microarrays prepared by immobilization of amino-functionalized glycans on NHS-activated glass slides have been successfully used to study protein-glycan interactions. Fluorescently tagged glycans with an amino functional group can be prepared from natural glycans released from glycoproteins. These tagged glycans

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