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M1523

Muscimol

Name: Muscimol
Brand: SIGMA
Price: 173 USD

≥98% (TLC), powder, GABAA receptor agonist.

Sinónimos:

3-Hydroxy-5-aminomethyl-isoxazole, 5-Aminomethyl-3-hydroxy-isoxazole, 5-Aminomethyl-3-isoxazolol, Agarine, Pantherine

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A ustedes/SKU	Disponibilidad	Precio
5 mg	Comprobar disponibilidad del carrito	$173.00
10 mg	Disponible para enviar HOYdesdeMILWAUKEE	$266.00
25 mg	Disponible para enviar HOYdesdeMILWAUKEE	$589.00

Acerca de este artículo

Fórmula empírica (notación de Hill):

C₄H₆N₂O₂

Número CAS:

2763-96-4

Peso molecular:

114.10

NACRES:

NA.77

PubChem Substance ID:

24896662

UNSPSC Code:

12352200

EC Number:

220-430-4

MDL number:

MFCD00057894

Beilstein/REAXYS Number:

1618960

Form:

powder

$173.00

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Servicio técnico

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Propiedades

Nombre del producto

Muscimol, powder

form

powder

Quality Segment

200

color

white to off-white

storage temp.

2-8°C

SMILES string

NCC1=CC(=O)NO1

InChI

1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)

InChI key

ZJQHPWUVQPJPQT-UHFFFAOYSA-N

Gene Information

rat ... Gabra2(29706)

Descripción

General description

Muscimol is a psychoactive isoxazole component, which is found in Amanita muscaria and related mushrooms. It lowers cerebral glucose metabolism and increases the level of 5-hydroxytryptamine in brain. Muscimol has hallucinogenic effects. It is associated with distorted perceptions, nausea and vomiting.

Application

Muscimol has been used:

to reduce conditioned fear-expression in lateral amygdala (LA)
to eliminate cortical cell response in ferrets
to inactivate lateral magnocellular nucleus of the nidopallium (LMAN) in zebra finches[1]

Biochem/physiol Actions

GABA_A receptor agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors and GABAC Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Este artículo	5.06044	PHL89495	G019
Sigma-Aldrich M1523 Muscimol	Sigma-Aldrich 5.06044 Muscimol	PHL89495 Muscimol	Sigma-Aldrich G019 Muscimol hydrobromide
form powder	form solid	form -	form solid
Quality Level 200	Quality Level 100	Quality Level -	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. 2-8°C
color white to off-white	color white	color -	color off-white to tan
Gene Information rat ... Gabra2(29706)	Gene Information -	Gene Information -	Gene Information human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

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pictograms

GHS06

signalword

Danger

hcodes

H300,H336

pcodes

P261 - P264 - P271 - P301 + P310 - P304 + P340 + P312 - P403 + P233

Hazard Classifications

Acute Tox. 2 Oral - STOT SE 3

target_organs

Central nervous system

Clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number

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