This IgG product exhibits variable domains and has not been sequenced. The material is isolated and purified by precipitation and affinity chromatography. Sequence information on human immunoglobulins is broadly available in published literature. As an example, please see the link below to review the NIH database which includes sequence information:
https://www.ncbi.nlm.nih.gov/protein/AAA02914.1
I2511
IgG from human serum
reagent grade, ≥95% (HPLC), buffered aqueous solution
Sinónimos:
IgG humana
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10 MG
$91.30
About This Item
application:
citations:
90
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conjugate
unconjugated
Quality Level
grade
reagent grade
assay
≥95% (HPLC)
form
buffered aqueous solution
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
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General description
IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections[1]
Human IgG is purified from normal human serum by precipitation and gel filtration techniques.
Human IgG is purified from normal human serum by precipitation and gel filtration techniques.
Application
Biochem/physiol Actions
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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The American journal of tropical medicine and hygiene, 72(6), 714-718 (2005-06-21)
Volunteers vaccinated with a candidate malaria vaccine containing merozoite surface protein 1(42) (MSP-1(42)) exhibit antibodies to MSP-1(42) that are measured by enzyme-linked immunosorbent assay (ELISA). The purpose of this study was to make a human reference standard for MSP-1(42) antibody
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Nucleic acid content can be quantified by flow cytometry through the use of intercalating compounds; however, measuring the presence of specific sequences has hitherto been difficult to achieve by this methodology. The primary obstacle to detecting discrete nucleic acid sequences
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D R McArthur et al.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 11(7), 775-782 (2008-08-12)
Trials investigating colorectal cancer (CRC) chemoprophylaxis with cyclooxygenase-2 (COX-2) inhibitors have been discontinued because of adverse cardiovascular effects. Nevertheless, identification of patients where beneficial, chemo-prophylactic effects of COX-2 inhibitors outweigh side-effects may be possible; this study aimed to investigate whether
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I would like to have the full amino acid sequence of the IgG from product I2511. I cannot find this information in any of the data sheets available online
1 answer-
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What is the shelf life of item A2661 after reconstitution?
1 answer-
The stock solution can be stored at -20°C for up to 3 months and can be aliquoted for sampling convenience.
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