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H1396

Sigma-Aldrich

Hexa-N-acetylchitohexaose

≥95%

Sinónimos:

NI, NII, NIII, NIV, NV, NVI-Hexaacetylchitohexaose

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About This Item

Fórmula empírica (notación de Hill):
C48H80N6O31
Número de CAS:
38854-46-5
Peso molecular:
1237.17
MDL number:
MFCD00210241
UNSPSC Code:
12352200
PubChem Substance ID:
24895458

assay

≥95%

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6NC(C)=O)[C@H](O)[C@H]5NC(C)=O)[C@H](O)[C@H]4NC(C)=O)[C@H](O)[C@H]3NC(C)=O)[C@H](O)[C@H]2NC(C)=O)[C@@H]1O

Substrates

Enhances protection against infection in mice by elevating cellular immunity; exhibits anti-tumor activity against solid tumors; elicits defense systems in plants; and serves as a substrate for human lysozyme.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Growth-inhibitory effect of hexa-N-acetylchitohexaose and chitohexaose against Meth-A solid tumor.
A Tokoro et al.
Chemical & pharmaceutical bulletin, 36(2), 784-790 (1988-02-01)
K Tsukada et al.
Japanese journal of cancer research : Gann, 81(3), 259-265 (1990-03-01)
N-Acetylchitohexaose, a water-soluble oligosaccharide was found to display a significant antimetastatic effect against Lewis lung carcinoma (LLC) transplanted into C57BL/6 mice, giving rise to a 40-50% inhibition ratio of pulmonary metastasis when administered intravenously (1 mg/kg) on day 6 after
T Usui et al.
Carbohydrate research, 203(1), 65-77 (1990-08-01)
A chitinase purified from culture filtrates of Trichoderma resei KDR-11 efficiently catalyzed a transglycosylation reaction on tetra-N-acetylchitotetraoside in a buffer medium containing ammonium sulfate, converting the tetrasaccharide into hexa-N-acetylchitohexaose (39.6%) and di-N-acetylchitobiose (55.7%) as the major products. Sugar-chain elongation from
M Kobayashi et al.
Microbiology and immunology, 34(5), 413-426 (1990-01-01)
A water-soluble oligosaccharide, N-acetylchitohexaose (NACOS-6), was able to enhance the protective effect against Candida albicans infection in mice during the early phase of tumor-bearing. A significant decrease in the number of C. albicans cells in the kidneys of NACOS-6-treated tumor-bearing
H H Felle et al.
Plant physiology, 124(3), 1373-1380 (2000-11-18)
Using ion-selective microelectrodes, the problem of how signals coming from symbiotic partners or from potential microbial intruders are distinguished was investigated on root hairs of alfalfa (Medicago sativa). The Nod factor, NodRm-IV(C16:2,S), was used to trigger the symbiotic signal and
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