H1254
8-Hydroxyquinoline glucuronide
≥95%, powder
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About This Item
Fórmula empírica (notación de Hill):
C15H15NO7
Número de CAS:
Peso molecular:
321.28
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
assay
≥95%
form
powder
color
light green
SMILES string
O[C@@H]1[C@H](O[C@H]([C@H](O)[C@H]1O)C(O)=O)Oc2cccc3cccnc23
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Substrates
Substrate for the histochemical demonstration of β-glucuronidase and for quantitative assay systems.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Andrew D Pris et al.
Analytical chemistry, 81(24), 9948-9954 (2009-11-18)
Enabling trace chemical detection equipment utilized in the field to transduce a biodetection assay would be advantageous from a logistics, training, and maintenance standpoint. Described herein is an assay design that uses an unmodified, commercial off-the-shelf (COTS) ion trap mobility
T P Monson et al.
International journal of radiation oncology, biology, physics, 20(6), 1263-1271 (1991-06-01)
RIF-1 mouse tumors express high levels of beta-glucuronidase activity relative to most normal tissues. The high activity can be exploited for targeting specific drugs preferentially to tumor tissues. In this study we examined the kinetics of 8-hydroxyquinoline (8-OHQ) accumulation in
Peter Tobin et al.
British journal of clinical pharmacology, 62(1), 122-129 (2006-07-18)
Irinotecan (CPT-11) is a prodrug that is used to treat metastatic colorectal cancer. It is activated to the topoisomerase poison SN-38 by carboxylesterases. SN-38 is metabolized to its inactive glucuronide, SN-38 glucuronide. The aim of this study was to determine
Direct radioiodination of metabolic 8-hydroxy-quinolyl-glucuronide, as a potential anti-cancer drug.
T Unak et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 47(7), 645-647 (1996-07-01)
8-Hydroxy-quinolyl-glucuronide (8-HOQ-Glu) can be deglucuronidated by the beta-glucoronidase enzyme, which has an activity that is considerably high in certain kinds of cancer cell. Owing to this enzyme activity, 8-HOQ-Glu can be considered as a potential anti-cancer drug. The combination of
F Dalet et al.
Journal of clinical microbiology, 33(5), 1395-1398 (1995-05-01)
A new commercial agar (Uricult-Trio) with 8-hydroxyquinoline-beta-glucuronide was used to assess 2,536 uropathogens for beta-glucuronidase activity typical of Escherichia coli. Included in the study were 1,807 strains of the family Enterobacteriaceae, 284 strains of nonfermentative bacilli, 345 strains of gram-positive
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