GW22756

Anti-Endoglin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• MDL number: MFCD01094408
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: chicken
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• manufacturer/tradename: Genway 15-288-22756
• technique(s): western blot: suitable
• NCBI accession no.: NP_000109.1
• UniProt accession no.: P17813
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ENG(2022)

Descripción

Immunogen

Immunogen Sequence: GI # 4557555, sequence 341-470

Recombinant endoglin

Application

Anti-Endoglin antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Endoglin is a type I transmembrane glycoprotein located on cell surfaces belonging to the transforming growth factor β superfamily. It is commonly referred to as CD105, END, HHT1 and ORW1. It is a part of the TGF β receptor complex, which plays an important role in angiogenesis. CD105 expression correlates with prognosis for several cancers and plays an important role in the pancreatic cancer microenvironment. Tumoral CD105 acts as an independent predictive marker for death risk. Mutation in endoglin causes a vascular defect, hereditary hemorrhagic telangiectasia (HHT1).

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)