F1428

Fenvalerate

≥97%

• Sinónimos: α-Cyano-3-phenoxybenzyl α-(4-chlorophenyl)­iso­valerate
• Fórmula empírica (notación de Hill): C₂₅H₂₂ClNO₃
• Número de CAS: 51630-58-1
• Peso molecular: 419.90
• Beilstein: 2025982
• Número MDL: MFCD00055324
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329799681
• NACRES: NA.77

Propiedades

• Nivel de calidad: 200
• Ensayo: ≥97%
• temp. de almacenamiento: −20°C
• cadena SMILES: CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3
• InChI: 1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3
• Clave InChI: NYPJDWWKZLNGGM-UHFFFAOYSA-N

Descripción

Descripción general

Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.[1]

Aplicación

Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.[2]

Acciones bioquímicas o fisiológicas

Piretroide de tipo II. Potente inhibidor de la calcineurina (proteína fosfatasa 2B).

Fenvalerate has good insecticidal potential and is less toxic to animals.[3] It might cause endocrine disruption and reproductive dysfunction in humans.[4] Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9.[1] In rat models it is found to hinder the action of mitochondrial enzymes.[3]

Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.

Nota de preparación

Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone.

Información de seguridad

• Pictogramas: GHS06,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H301,H315,H319,H335,H410
• Consejos de prudencia: P261 - P264 - P273 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable