D6446

DOV 216,303

≥98% (HPLC)

• Sinónimos: (±)-1-(3,4-dichlorophenyl)-3-azabicyclo-[3.1.0]hexane hydrochloride
• Fórmula empírica (notación de Hill): C₁₁H₁₁Cl₂N · HCl
• Número de CAS: 86215-36-3
• Peso molecular: 264.58
• MDL number: MFCD06407666
• UNSPSC Code: 12352200
• PubChem Substance ID: 329798827
• NACRES: NA.77

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: ≥10 mg/mL
• originator: Merck & Co., Inc., Kenilworth, NJ, U.S.
• storage temp.: −20°C
• SMILES string: Cl.Clc1ccc(cc1Cl)C23CNCC2C3
• InChI: 1S/C11H11Cl2N.ClH/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11;/h1-3,8,14H,4-6H2;1H
• InChI key: KAGBHVBIOJBGBD-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Triple reuptake inhibitor (TRI); serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI); IC50 values of ~20, 14, and 78 nM, respectively.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H319
• pcodes: P301 + P310 + P330 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable