D2945

Anti-DCDC2 antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-DCDC2A, Anti-Doublecortin domain containing 2, Anti-RU2, Anti-RU2S
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~55 kDa; antigen ~70 kDa
• species reactivity: human
• enhanced validation: recombinant expression; Learn more about Antibody Enhanced Validation
• concentration: ~1.5 mg/mL
• technique(s): western blot: 1-2 μg/mL using HEK-293T cell lysate expressing human DCDC2
• UniProt accession no.: Q9UHG0
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... DCDC2(51473)

Descripción

General description

DCDC2 belongs to the doublecortin (DCX) superfamily and contains two doublecortin domains. DCDC2 is expressed in fetal and adult CNS.

Application

Anti-DCDC2 antibody produced in rabbit is suitable for western blot analysis at a working concentration of 1-2μg/mL using a HEK-293T cell lysate expressing human DCDC2.

Biochem/physiol Actions

DCDC2 is one of the dyslexia susceptibility genes involved in neuronal migration and other developmental processes. The DCX domain of DCDC2 binds tubulin and enhances microtubule polymerization. Several SNPs within the DCDC2 gene have been associated with dyslexia. It modulates neuronal development in the brain.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)