D0444
DT-2 trifluoroacetate salt
≥95% (HPLC), film
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Seleccione un Tamaño
250 μG
$201.00
Seleccione un Tamaño
Cambiar Vistas
250 μG
$201.00
About This Item
Fórmula empírica (notación de Hill):
C122H223N53O23 · xC2HF3O2
Peso molecular:
2800.42 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
Productos recomendados
Quality Level
assay
≥95% (HPLC)
form
film
composition
Peptide content, ≥60%
color
colorless to white
solubility
H2O: 0.5 mg/mL, clear
shipped in
wet ice
storage temp.
−20°C
Amino Acid Sequence
Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Leu-Arg-Lys-Lys-Lys-Lys-Lys-His-NH2
Biochem/physiol Actions
Cell permeable cGMP protein kinase (PKG) inhibitor
Features and Benefits
This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Mark S Taylor et al.
Molecular pharmacology, 65(5), 1111-1119 (2004-04-23)
Cyclic GMP-dependent protein kinase (PKG) serves as an important physiological regulator of vascular reactivity and tone. However, available inhibitors of PKG have exhibited variable effects in intact tissue, hindering the elucidation of the functional role of PKG in blood vessels.
W R Dostmann et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(26), 14772-14777 (2000-12-20)
Arrays of octameric peptide libraries on cellulose paper were screened by using (32)P-autophosphorylated cGMP-dependent protein kinase Ialpha (cGPK) to identify peptide sequences with high binding affinity for cGPK. Iterative deconvolution of every amino acid position in the peptides identified the
Christin Christensen et al.
Stem cells and development, 15(5), 647-654 (2006-11-16)
Previously, we have shown that increasing the intracellular cGMP concentration enhances the sonic hedgehog (Shh) response in neural plate cells. The use of two mouse embryonic stem (ES) cell lines allowed a highly sensitive and reproducible quantification of the Shh
Artículos
Our offers many products related to PKA & PKG for your research needs.
Active Filters
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico
