C4582

β-Carotene

synthetic, ≥95% (HPLC), crystalline

• Sinónimos: β,β-Carotene, Provitamin A
• Fórmula empírica (notación de Hill): C₄₀H₅₆
• Número de CAS: 7235-40-7
• Peso molecular: 536.87
• Beilstein: 1917416
• Número CE: 230-636-6
• Número MDL: MFCD00001556
• Código UNSPSC: 12352212
• ID de la sustancia en PubChem: 24892702
• NACRES: NA.77

Propiedades

• origen biológico: synthetic
• Nivel de calidad: 200
• Ensayo: ≥95% (HPLC)
• Formulario: crystalline
• impurezas: α-carotene, essentially free
• color: dark red-purple to red-brown
• mp: 178-179 °C
• solubilidad: hexane: soluble 100 μg/mL; DMSO: 30 μg/mL; H₂O: insoluble
• ε (coeficiente de extinción): 2160-2280 at 478-479 nm in hexane at 1% (vs. 2280, lit.); 2450-2590 at 450-452 nm in hexane at 1% (vs. 2590, lit.)
• temp. de almacenamiento: −20°C
• cadena SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1
• InChI: 1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
• Clave InChI: OENHQHLEOONYIE-JLTXGRSLSA-N

Descripción

Aplicación

β-Carotene has been used:

• as standard for quantification of b-carotene using HPLC analysis[1]
• as a standard for the identification and quantification of authentic standards for carotenoid groups[2]
• for standard curve preparation in the measurement of β-carotene production[3]
• for standard curve preparation in nutritive assays[4]

Acciones bioquímicas o fisiológicas

β-Carotene (pro-vitamin A) is a member of carotenoids. This antioxidant plays a vital role in human physiology.[5] β-Carotene is an abundant carotenoid. It is considered as a precursor of vitamin A, which is a lipid soluble antioxidant with vitamin E properties.[5][6]

The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.

The most important of the provitamins A.

Precaución

Purchase minimum quantity required. Discard one month after opening.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 217.9 °F - closed cup
• Punto de inflamabilidad (°C): 103.3 °C - closed cup
• Equipo de protección personal: Eyeshields, Gloves