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MilliporeSigma

C222

Sigma-Aldrich

Cathine hydrochloride

≥97.5% (HPLC), powder, anorexic

Sinónimos:

threo-2-Amino-1-hydroxy-1-phenyl propane hydrochloride, Pseudonorephedrine hydrochloride, S,S-Norpseudoephedrine hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C9H13NO · HCl
Número de CAS:
Peso molecular:
187.67
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

product name

Cathine hydrochloride,

form

powder

Quality Level

drug control

USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

storage condition

desiccated

color

white to off-white

mp

172-175 °C

solubility

H2O: 15 mg/mL, clear
0.1 M HCl: soluble
ethanol: soluble

application(s)

forensics and toxicology

SMILES string

Cl[H].C[C@H](N)[C@@H](O)c1ccccc1

InChI

1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7,9,11H,10H2,1H3;1H/t7-,9+;/m0./s1

InChI key

DYWNLSQWJMTVGJ-DKXTVVGFSA-N

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Biochem/physiol Actions

Anorexic; with pharmacological effects similar to those of the amphetamines.

Caution

Photosensitive

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificados de análisis (COA)

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E A Pehek et al.
Pharmacology, biochemistry, and behavior, 36(2), 267-271 (1990-06-01)
The effects of the psychostimulant (+)cathine (norpseudoephedrine) were examined in a two-choice, food-motivated, drug-discrimination paradigm. Rats were able to discriminate cathine from vehicle and this effect was dose- and time-dependent. Prior administration of cathine resulted in a diminished response (tolerance)
M B Ahmed et al.
Journal of ethnopharmacology, 39(3), 213-216 (1993-08-01)
Catha edulis is a plant that grows in certain areas of East Africa and the Arab Peninsula. The stimulating properties of fresh material were described more than seven centuries ago and today the habit of inducing a state of euphoria
Osquel Barroso et al.
Drug testing and analysis, 4(5), 320-329 (2011-05-07)
Due to its stimulatory effects on the central nervous system, and its structural similarity to banned stimulants such as ephedrine and methamphetamine, pseudoephedrine (PSE) at high doses is considered as an ergogenic aid for boosting athletic performance. However, the status
E Oyungu et al.
East African medical journal, 84(5), 219-225 (2007-09-26)
Khat is a plant whose young shoots and leaves are habitually used in Eastern Africa and the Arabian Peninsula as a drug of recreation. Although it is used without any control in these regions, it contains two controlled substances, cathinone
Raz Krizevski et al.
Journal of ethnopharmacology, 114(3), 432-438 (2007-10-12)
Khat (Catha edulis Forsk., Celastraceae) is a perennial shrub that was introduced to Israel by Yemenite immigrants. Khat young leaves are chewed as a stimulant. The main stimulating active principles in this plant are the phenylpropylamino alkaloids (-)-cathinone [(S)-alpha-aminopropiophenone], (+)-cathine

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