C159

Calphostin C from Cladosporium cladosporioides

• Sinónimos: UCN-1028c
• Fórmula empírica (notación de Hill): C₄₄H₃₈O₁₄
• Número CAS: 121263-19-2
• Peso molecular: 790.76
• UNSPSC Code: 12352204
• MDL number: MFCD00133155

Propiedades

• storage temp.: −20°C
• SMILES string: COc1cc(O)c2C(=O)C(OC)=C(CC(C)OC(=O)Oc3ccc(O)cc3)c4c5C(CC(C)OC(=O)c6ccccc6)=C(OC)C(=O)c7c(O)cc(OC)c(c57)c1c24
• InChI: 1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45-47H,16-17H2,1-6H3
• InChI key: SRJYZPCBWDVSGO-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Highly specific inhibitor of protein kinase C (IC₅₀ = 50 nM); requires light for activation. At higher concentrations (100 nM or greater), it has been shown to inhibit cell proliferation and induce apoptosis in vitro.

Información de seguridad

• Clase de almacenamiento: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)